Bidisha Biswas Basu,Priyanka M Lal,Shreya Sengupta,




Carcinoma cervix,Colposcopy biopsy,Cytopathological examination Evaluation,Pap Smear,


Cervical cancer is the fourth most common cancer in women. In 2018, an estimated 570,000 women were diagnosed with cervical cancer worldwide and about 311,000 women died from the disease. It is the most common genital cancer among women in India. Pap smear is very useful in detecting abnormal cells and colposcopy locates the abnormal lesion when pap smear is abnormal. The objective of the study is to evaluate the women coming to the Gynaecology Outpatient Department undergoing pap smear and follow-up of abnormal smear using colposcopy. 103 women in the age group of 26-75(50.29+2.56) years who attended the gynecology outpatient department (GOPD)at a tertiary care teaching hospital in central Kerala with various clinical symptoms were screened by pap smear testing over two weeks. The smear was obtained using an Ayre spatula and it was spread over a glass slide which was placed in 95% ethyl alcohol in a coplin Jar. It was then sent to the department of pathology for cytopathological examination followed up using colposcopy and biopsy was done in the cases with abnormal colposcopy. Among these women,46.6 percentage have a normal pap smear 47.6% have an abnormal smear, and 5. 8 % have an atrophic smear. Among abnormal smear 4.8% are ASCUS, 1.9% LSIL, 0.97% SCC, 0.97% high-grade adenocarcinoma, and 37.86% inflammatory smears. As per International guidelines, women with abnormal pap smear tests should undergo colposcopy and those with abnormal colposcopy findings should undergo biopsy. Awareness about cancer should be increased and women should be motivated to undergo screening.


I. Ashok Verma, Suresh Verma, Shivani Vashest, Sumit Altri, Amrita Singhal, : “A study on cervical cancer screening in symptomatic women using paps smear in a tertiary care hospital in rural area of Himachal Pradesh, India.” Middle East fertility Society Journal. (2017) 22, 39-42
II. Bijoy Sree Sen Gupta, Sisir K Chattopadhyay, Thankam P Varma. : “Gynaecology for post graduate and practioners.” Second edition. Chapter 47 p.no.634-35
III. Howkins and Bourne Shaw’s textbook of Gynaecology,17th edition.
IV. Integrating HPV testing in cervical screening programs, Pan American health organization.https://wnow.paho.org
V. Mayank Singh, Ravi Prakash Jha, Deepak Dhamnetiya, : “Secular trends in incidence and mortality of cervical cancer in India and its States,1990-2019: data from the global burden of disease 2019 study.” 7th Feb 2022 BMC cancer 22, article number: 149( 2022)
VI. Meenakshi Venkatesh, Usha Devi Gopalan, : “A comparative study of pap smear and colposcopy guided biopsy in the evaluation of unhealthy cervix.” International journal of reproduction, volume 9, No. 6(2020) June 2020.https://doi.org/10.18203/23201770.ijrcog20202301
VII. Nayar,: “The Bethesda System for reporting cervical cytology.” 3rd edition,2015
VIII. Paul Uchizi Kasika, Alfred Kajira et al, : “Histopathological profile of cervical biopsies in Northern Malawi: retrospective cross sectional study BMJ”, Google scholar vol12, issue 3
IX. Poil U R, Bidinger P D, : “Visual inspection with acetic acid (VIA)screening program: 7 years experience in early detection of cervical cancer and precancers in rural South India.” Indian J community medicine 2015; 40(3): 203
X. Priyanka Poonam. Role of pap smear in detection of pre cancerous lesions of cervix -a case study, IAIM, 2019; 6(2)44-47
XI Push Lata Sachan, Meenakshi Singh, Rekha Sachan, : “A study on screening using pap smear test and clinical correlation”. Asia Pacific Journal of Oncology Nursing.Vol.5, Issue 3, P337-41, July 2018. https://ncbi.nlm.nik.gov
XII. Reaching 2020 Cervical cancer elimination targets. World Health Organization. https://www.who.int >…> detail
XIII. Saslow P, Solomon P, Lawson H W, Killackey M, Kulasingam S L, Cain J, et al., : American Cancer society, American society for colposcopy and cervical pathology and American society for clinical pathology
XIV. Screening guidelines for the prevention and early detection of cervical cancer – CA cancer J cin 2012;62:147-72 (pubmed) (Google scholar)
XV. Singh P., Ilancheran A. : “The ‘pap’ or cervical smear and the role of colposcopy in screening for carcinoma of cervix.” : Singapore Med J. 1989 June; 30 (3) : 302-5
XVI. Syeda Rumman Aktar Siddiqui, M Ariful Islam, M Zillur Rahman, : “Diagnosis of cervical lesion by colposcopy, VIA, pap smear test and their correlation with histopathology in a tertiary level laboratory in chattogram”. Bangladesh international Journal of research in medicine Vol .11, No. 3( 2023 ) March 2023
XVII. Yasamin Hamza Sharif, : “Clinical correlation of cc screening using Pap Smear test.” Journal of population therapeutics and clinical pharmacology. vol 29, number 01 (2022) JPTCP

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